The field of "computational cryopreservation" deals with the usage of computational methods in cryopreservation protocols. Currently, there is very little computational work done that can be applied to improve post-thaw cell and tissue quality. Novel and innovative approaches are required to speed up the optimisation of cryopreservation protocols. Ultimately, one major goal would be to have a generic computational tool that can be used together with experimental work to generate custom and optimal cryopreservation processes for cells, tissues and organs.
In this recent article, I express some thoughts on the usage of computational modelling and analysis in tissue cryopreservation (including neural tissue).